previous  nextY10936.T14.710 (FBXO46) -> ENSG00000177051@66_37.T14.46214701
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Tract / statusT14, reported length 13 / uMNR3   MNR_ensembl
First published byWOERNER2001 PubMed
Accession numberY10936 gi:2143253
Gene (chromosome)FBXO46  ( 19 )   SOURCE
alt. namesHPDMPK
EnsemblENSG00000177051   SMART   GermOnline   GeneCards
NCBIEntrez Gene 23403   Unigene Hs.128702 (SAGE)   GeneCards 23403 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
95.2100.091.7100.0
(n=21)(n=10)(n=12)(n=15)

Genomic sequence
BLAST WWW
BLAST local
CCGCCTGCCC ATTCCCCTAC TCCAGGCAGC ATTGATCCCT CACCGGAACT GAGCTGGGGT TCAGCAGGGG TGACCCAGGA AAGCCCTCTG CTTGATCCTG TTGATTTTCT ACTCTTCAGA ACCAGGGCCG TGGACCCTCT GAGAAGGGTG TTTTTTTTTT TTTTATCAGC ATCTCACTTT CTTCTCCATT CAGCCCCAAC CCCCTCCCTG CCATGCTTTC CACCCCAAGG ACCCACCAGC AGGGAGCAGA CGGCAGCTAA TTTTGGTACC ACTTAAGGGT CCCCCCATTC TGGCCCCCAT CCTCTCCCTC ACCC
MNR, transcribed, primer.
PCR system1sense gCTTgATCCTgTTgATTTTCTACTC, antisense CTgAATggAgAAgAAAgTgAgATg, product length 104, Ta 60.
Transcript sequenceCCGCCTGCCC ATTCCCCTAC TCCAGGCAGC ATTGATCCCT CACCGGAACT GAGCTGGGGT TCAGCAGGGG TGACCCAGGA AAGCCCTCTG CTTGATCCTG TTGATTTTCT ACTCTTCAGA ACCAGGGCCG TGGACCCTCT GAGAAGG--- -TTTTTTTTT TTTTATCAGC ATCTCACTTT CTTCTCCATT CAGCCCCAAC CCCCTCCCTG CCATGCTTTC CACCCCAAGG ACCCACCAGC AGGGAGCAGA CGGCAGCTAA TTTTGGTACC ACTTAAGGGT CCCCCCATTC TGGCCCCCAT CCTCTCCCTC ACCC
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST00000539236003329411531ENSP00000441134show
2ENST0000031768310124193629902163ENSP00000410007show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: uMNR3 (uMNR3) .

Culture data cell line   mutated   allele(s)  reference
Co115 1 m5m3 INTERN9999
Colo60H 1 m4 INTERN9999
HCT116 1 m3 WOERNER2001
KM12 1 m5m3 WOERNER2001
LoVo 1 m5m2 WOERNER2001
LS174T 1 m4m1 WOERNER2001
LS180 1 m4m1 WOERNER2001
RKO 1 m4p2 INTERN9999
SW48 1 m4m3 WOERNER2001
TC7 1 m2 INTERN9999

1 primers derived from WOERNER2001.

SelTarbase version latest, release 201307, last updated 20130701.

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