previous  nextY00285.G8.4089 (IGF2R) -> ENSG00000197081@66_37.G8.160485488
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Tract / statusG8 / cMNR -> Tx!   MNR_ensembl
First published bySOUZA1996A PubMed
Accession numberY00285 gi:33054
Gene (chromosome)IGF2R  ( 6 )   SOURCE
alt. namesIGF2R;IGFR2
EnsemblENSG00000197081   SMART   GermOnline   GeneCards
NCBIEntrez Gene 3482   Unigene Hs.487062 (SAGE)   GeneCards 3482 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
20.322.716.018.7
(n=1347)(n=22)(n=324)(n=561)

Genomic sequence
BLAST WWW
BLAST local
CACTCTTCAG GGTGTGTGGT GTCACATGTC TTAGGCTAAG TTTGACAGCC TAGGGACCCG AACCAAACCT TGTTTAATGT TCTCCTTCTT TACAGGTCTC CTGACTCAGA AGCTAACTTA TGAAAATGGC TTGTTAAAAA TGAACTTCAC GGGGGGGGAC ACTTGCCATA AGGTTTATCA GCGCTCCACA GCCATCTTCT TCTACTGTGA CCGCGGCACC CAGCGGGTGA GCATGTACCG ACGGCCCTCA GCGGGGTCTT CTCCCCACCC TCAGGCTGCT GGGATCATAT TAGAAAGAAT CTGTCCTC
MNR, transcribed, primer.
PCR system1sense gCAggTCTCCTgACTCAgAA, antisense gAAgAAgATggCTgTggAgC, product length 111, Ta 61.
Transcript sequenceGCTTTCCTCA GACGTCTGCC CCACAAGTGA CAAGTCCAAG GTGGTCTCCT CATGTCAGGA AAAGCGGGAA CCGCAGGGAT TTCACAAAGT GGCAGGTCTC CTGACTCAGA AGCTAACTTA TGAAAATGGC TTGTTAAAAA TGAACTTCAC GGGGGGGGAC ACTTGCCATA AGGTTTATCA GCGCTCCACA GCCATCTTCT TCTACTGTGA CCGCGGCACC CAGCGGCCAG TATTTCTAAA GGAGACTTCA GATTGTTCCT ACTTGTTTGA GTGGCGAACG CAGTATGCCT GCCCACCTTT CGATCTGA
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST0000035695611149762590914090ENSP00000349437show
2ENST0000046463600570--
3ENST0000047943400544--
4ENST0000048760700359--
5ENST0000047583400758--
6ENST0000047558400597--
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: cMNR (cMNR) .

Culture data cell line   mutated   allele(s)  reference
Co115 1 wtp1* GAYET2001 / *INTERN9999
Colo60H 0 wt INTERN9999
DLD1 0 - KU1999
HCT116 0 - KU1999
HCT15 0 - GAYET2001
HCT8/HRT18 0 - KU1999
KM12 1 wtp1 WOERNER2001
LoVo 0 - KU1999
LS174T 0 - KU1999
LS180 0 wt WOERNER2001
RKO 0 wt ELBCHIRI2005
SNU-1040 0 - KU1999
SNU-1047 1 - KU1999
SNU-175 0 - KU1999
SNU-407 0 - KU1999
SNU-769A 0 - KU1999
SNU-769B 0 - KU1999
SNU-C2A 1 - KU1999
SNU-C4 0 - KU1999
SW48 1 m1wt* CARETHERS2000 / *WOERNER2001
TC7 0 - GAYET2001
TC71 0 - GAYET2001

Show consequences concerning peptide sequence(s) of frameshift alleles m2/m1/p1/p2.


1 primers derived from SOUZA1996A.

SelTarbase version latest, release 201307, last updated 20130701.

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