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Tract / statusT15, reported length 14 / uMNR3   MNR_ensembl
First published byWOERNER2001 PubMed
Accession numberU79260 gi:1710215
Gene (chromosome)FTO  ( 16 )   SOURCE
alt. namesU79260;FATSO;MGC5149
EnsemblENSG00000140718   SMART   GermOnline   GeneCards
NCBIEntrez Gene 79068   Unigene Hs.528833 (SAGE)   GeneCards 79068 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
81.8100.041.76.7
(n=22)(n=11)(n=12)(n=15)

Genomic sequence
BLAST WWW
BLAST local
CACAGATGGG GCACCCTCGG GCCATCCAGC CCAGTGTTTT CTTTAGCCCC TATGATGTTC ATTTTTTGTT ATATCCCATT AGGTGCCCAT ATTTAAAAAT TGGGAGATTT CACATAAAAT TAAAAGGTCT GCATTTTCTT TTTTCTTTTC TTTTTTTTTT TTTTTGAGAC ACAGTCTCAC TCTGTCACCA GGCTAGAGTG CAGTGGCACG ATCTCAGCTC ACTGCAACCT CTGCCTCCCA GGTTCAAGTA ATTCTCCTGC CTCAGCCTCC CAAGTAGCTG GGACTACAGG CACGTGCCAC CACGCCCAGC TAATT
MNR, transcribed, primer.
PCR system1sense TTTgTTATATCCCATTAggTgCC, antisense AgCCTggTgACAgAgTgAgAC, product length 130, Ta 59.
Transcript sequenceCACAGATGGG GCACCCTCGG GCCATCCAGC CCAGTGTTTT CTTTAGCCCC TATGATGTTC ATTTTTTGTT ATATCCCATT AGGTGCCCAT ATTTAAAAAT TGGGAGATTT CACATAAAAT TAAAAGGTCT GCATTTTCTT TTTTCTTTTC TTTTTTTTTT TTTTTGAGAC ACAGTCTCAC TCTGTCACCA GGCTAGAGTG CAGTGGCACG ATCTCAGCTC ACTGCAACCT CTGCCTCCCA GGTTCAAGTA ATTCTCCTGC CTCAGCCTCC CAAGTAGCTG GGACTACAGG CACGTGCCAC CACGCCCAGC TAATT
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST00000471389102231741117663637ENSP00000418823show
2ENST000004640710042171065ENSP00000418424show
3ENST0000043161000164485707ENSP00000415636show
4ENST00000460382001254461517ENSP00000417422show
5ENST000004638551012550930562405ENSP00000417843show
6ENST00000268349106925227992148ENSP00000268349show
7ENST0000047283500847--
8ENST00000394647002648941065ENSP00000378142show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: uMNR3 (uMNR3) .

Culture data cell line   mutated   allele(s)  reference
Co115 1 m4m3 WOERNER2001
Colo60H 1 m3 WOERNER2001
HCT116 1 m4m3 WOERNER2001
KM12 1 m3 WOERNER2001
LoVo 1 m1 WOERNER2001
LS174T 1 m3m2 WOERNER2001
LS180 1 m3m2m1 WOERNER2001
RKO 1 m3m2 WOERNER2001
SW48 1 m2 WOERNER2001
TC7 1 m1wt INTERN9999
TC71 1 m2m1 INTERN9999

1 primers derived from WOERNER2001.

SelTarbase version latest, release 201307, last updated 20130701.

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