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Tract / statusA10 / cMNR -> Tx!   MNR_ensembl
First published byMIRONOV1999 PubMed
Accession numberU76308 gi:1666239
Gene (chromosome)ATR  ( 3 )   SOURCE
alt. namesATRMRNA;FRP1
EnsemblENSG00000175054   SMART   GermOnline   GeneCards
NCBIEntrez Gene 545   Unigene Hs.271791 (SAGE)   GeneCards 545 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
24.523.57.320.6
(n=326)(n=17)(n=274)(n=194)

Genomic sequence
BLAST WWW
BLAST local
ATGTTTTATC TGACAAGTTC TTTAACAGAA CCTTTCTCTG AACACGGACA TGTGGACCTC TTCTGTAGGA ACTTGAAAGC CACTTCTCAA CATGAATGTT CATCTTCTCA ACTAAAAGCT TCTGTCTGCA AGCCATTCCT TTTCCTACTG AAAAAAAAAA TACCTAGTCC AGTAAAACTT GGTGAGTGAT TATGACTTAT TTAATACTTT AAAACCTATT TAAGCTCTGC TTTTCAAATC AGTAAAAGAA TTAGACTGAA GCCTTGAAAA ATTACAGGAA GTTACATGCT TTATAGATTC AGTGCTCAGT
MNR, transcribed, primer.
PCR system1sense TCTTCTgTAggAACTTgAAAgCC, antisense TgAAAgCAAgTTTTACTggACTAgg, product length 129, Ta 60.
Transcript sequenceATGTTTTATC TGACAAGTTC TTTAACAGAA CCTTTCTCTG AACACGGACA TGTGGACCTC TTCTGTAGGA ACTTGAAAGC CACTTCTCAA CATGAATGTT CATCTTCTCA ACTAAAAGCT TCTGTCTGCA AGCCATTCCT TTTCCTACTG AAAAAAAAAA TACCTAGTCC AGTAAAACTT GCTTTCATAG ATAATCTACA TCATCTTTGT AAGCATCTTG ATTTTAGAGA AGATGAAACA GATGTAAAAG CAGTTCTTGG AACTTTATTA AATTTAATGG AAGATCCAGA CAAAGATGTT AGAGTGGCTT
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST00000504521001244718ENSP00000422553show
2ENST00000515810001121553ENSP00000421870show
3ENST0000035072111123805882492433ENSP00000343741show
4ENST0000051329100213765190ENSP00000424355show
5ENST0000051510700546--
6ENST0000051101600681--
7ENST00000514393001154552ENSP00000424754show
8ENST0000050762000837--
9ENST0000051586300641--
10ENST00000515149001931929ENSP00000425897show
11ENST000005071480021324724ENSP00000426595show
12ENST0000038310111123786680562241ENSP00000372581show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: cMNR (cMNR) .

Culture data cell line   mutated   allele(s)  reference
Co115 1 m1wt WOERNER2001
Colo60H 1 m1wt WOERNER2001
DLD1 0 - MIRONOV1999
HCA7 0 wt ABDELRAHMAN2008A
HCT116 0 - MIRONOV1999
HCT15 0 - MIRONOV1999
HCT8/HRT18 0 - LI2004A
KM12 0 wt WOERNER2001
LIM1215 0 wt ABDELRAHMAN2008A
LoVo 0 wt WOERNER2001
LS174T 0 - MIRONOV1999
LS180 0 - MIRONOV1999
LS411 1 - LI2004A
RKO 0 wt WOERNER2001
SW48 0 wt WOERNER2001
TC7 0 wt ELBCHIRI2005
TC71 1 mwt ELBCHIRI2005

Show consequences concerning peptide sequence(s) of frameshift alleles m2/m1/p1/p2.


1 primers derived from WOERNER2001.

SelTarbase version latest, release 201307, last updated 20130701.

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