previous  nextU29874.C9.4305 (FLT3LG) -> ENSG00000090554@66_37.C9.49982166
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Tract / statusC9 / cMNR -> Tx!   MNR_ensembl
First published byWOERNER2001 PubMed
Accession numberU29874 gi:1072036
Gene (chromosome)FLT3LG  ( 19 )   SOURCE
EnsemblENSG00000090554   SMART   GermOnline   GeneCards
NCBIEntrez Gene 2323   Unigene Hs.428 (SAGE)   GeneCards 2323 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
35.758.825.033.3
(n=28)(n=17)(n=12)(n=15)

Genomic sequence
BLAST WWW
BLAST local
AAAAAAATTA ATTAATTAAA TAAATAAACT CTGAGAGCCA GAGCTCACTG GGCCCTGTTG CTGGGCATCG CCAGCAGGGA AGGGCCTTTG GCCTGCGGAG GGGCGGTGGG GGGATGACGT GGTGGTGACG TCTCCCTCCC CTGCTCCCAG CCCCCCCCCA GCTGTCTTCG CTTCGTCCAG ACCAACATCT CCCGCCTCCT GCAGGAGACC TCCGAGCAGC TGGTGGCGCT GAAGCCCTGG ATCACTCGCC AGAACTTCTC CCGGTGCCTG GAGCTGCAGT GTCAGCCCGG TAAAGGCTTC CAGGCACCC
MNR, transcribed, primer.
PCR system1sense gggATgACgTggTggTg, antisense gTgATCCAgggCTTCAgC, product length 135, Ta 62.
Transcript sequenceCAGGACGAGG AGCTCTGCGG GGGCCTCTGG CGGCTGGTCC TGGCACAGCG CTGGATGGAG CGGCTCAAGA CTGTCGCTGG GTCCAAGATG CAAGGCTTGC TGGAGCGCGT GAACACGGAG ATACACTTTG TCACCAAATG TGCCTTTCAG CCCCCCCCCA GCTGTCTTCG CTTCGTCCAG ACCAACATCT CCCGCCTCCT GCAGGAGACC TCCGAGCAGC TGGTGGCGCT GAAGCCCTGG ATCACTCGCC AGAACTTCTC CCGGTGCCTG GAGCTGCAGT GTCAGCCCGA CTCCTCAACC CTGCCACCC
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST0000020463711917991035437ENSP00000204637show
2ENST000003440191191628627437ENSP00000341305show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: cMNR (cMNR) .

Culture data cell line   mutated   allele(s)  reference
Co115 1 wtp1 WOERNER2001
Colo60H 1 wtp1p2 WOERNER2001
DLD1 0 wt KIM2013C
HCT116 1 wt WOERNER2001
HCT8/HRT18 0 wt KIM2013C
KM12 0 p1p2 WOERNER2001
LoVo 1 wtp1 WOERNER2001
LS174T 0 wt WOERNER2001
LS180 0 wt WOERNER2001
RKO 1 wtp1 WOERNER2001
SNU-407 0 wt KIM2013C
SNU-C2A 1 wtp1 KIM2013C
SNU-C2B 0 wt KIM2013C
SNU-C4 1 wtp1 KIM2013C
SW48 1 wtp1 WOERNER2001
TC7 1 wtp1 INTERN9999
TC71 1 m1wt INTERN9999

Show consequences concerning peptide sequence(s) of frameshift alleles m2/m1/p1/p2.


1 primers derived from WOERNER2001.

SelTarbase version latest, release 201307, last updated 20130701.

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