previous  nextU28015.A10.179 (CASP5) -> ENSG00000137757@66_37.A10.104878041
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Tract / statusA10 / cMNR -> Tx!   MNR_ensembl
First published bySCHWARTZS1999 PubMed
Accession numberU28015 gi:975300
Gene (chromosome)CASP5  ( 11 )   SOURCE
alt. namesCASP5
EnsemblENSG00000137757   SMART   GermOnline   GeneCards
NCBIEntrez Gene 838   Unigene Hs.213327 (SAGE)   GeneCards 838 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
47.690.511.438.6
(n=458)(n=21)(n=88)(n=140)

Genomic sequence
BLAST WWW
BLAST local
GATGTGTGTT ATTCGCTGGA GACATGGTAA AATAGAATGT ATTTTTAGAG GAGTTTCATA TTACAGAGTT ATGTCTTAGG TGAAGGCAGA ACTCTTTAAG CTGTGCCCAT AGTTAAAGGA GTCTTTCTAT TTCTGACAGA AGACAACCAC AAAAAAAAAA CAGTTAAGAT GTTGGAATAC CTGGGCAAAG ATGTTCTTCA TGGTGTTTTT AATTATTTGG CAAAACACGA TGTTCTGACA TTGAAGGAAG AGGAAAAGAA AAAATATTAT GATACCAAAA TTGAAGACAA GGCCCTGATC TTGGTAGACT
MNR, transcribed, primer.
PCR system1sense CAgAgTTATgTCTTAggTgAAgg, antisense ACCATgAAgAACATCTTTgCCCAg, product length 141, Ta 59.
Transcript sequenceGAAGCTATGT TCAAAGGTAT CCTTCAGAGT GGATTGGATA ACTTCGTGAT AAACCACATG CTAAAGAACA ACGTGGCTGG ACAAACATCT ATCCAGACCC TAGTACCTAA TACGGATCAA AAGTCGACCA GTGTAAAAAA AGACAACCAC AAAAAAAAAA CAGTTAAGAT GTTGGAATAC CTGGGCAAAG ATGTTCTTCA TGGTGTTTTT AATTATTTGG CAAAACACGA TGTTCTGACA TTGAAGGAAG AGGAAAAGAA AAAATATTAT GATACCAAAA TTGAAGACAA GGCCCTGATC TTGGTAGACT
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST00000438448003357535ENSP00000396053show
2ENST0000026031511113061414193ENSP00000260315show
3ENST0000044474911321163123750ENSP00000388365show
4ENST0000052605611113451344232ENSP00000436877show
5ENST00000531367001880879ENSP00000434471show
6ENST0000045620011132897919ENSP00000408455show
7ENST0000045609411129627623273ENSP00000415241show
8ENST00000393141113313771488264ENSP00000376849show
9ENST0000041843400339121023ENSP00000398130show
10ENST00000393139111715731378264ENSP00000376847show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: cMNR (cMNR) .

Culture data cell line   mutated   allele(s)  reference
Co115 1 m1wt* GAYET2001 / *INTERN9999
Colo60H 1 m1wt INTERN9999
DLD1 1 m1wt OFFMAN2005
HCA7 1 wtp1 WILLIAMS2010
HCT116 1 m1wt WOERNER2001
HCT15 1 mwt* GAYET2001 / *ELBCHIRI2005
KM12 0 wt WOERNER2001
LIM1215 1 m1 WILLIAMS2010
LIM1899 1 m1wt WILLIAMS2010
LIM2405 1 m2m1 WILLIAMS2010
LIM2408 1 m2m1 WILLIAMS2010
LIM2537 1 m2wt WILLIAMS2010
LIM2550 1 m1wt WILLIAMS2010
LIM2551 1 m2wt WILLIAMS2010
LoVo 1 m1wt WOERNER2001
LS174T 1 m1 WOERNER2001
LS180 1 m1 WOERNER2001
RKO 0 wt INTERN9999
SW48 1 m1wt WOERNER2001
TC7 1 m1wt* GAYET2001 / *INTERN9999
TC71 1 m1wt* GAYET2001 / *INTERN9999

Show consequences concerning peptide sequence(s) of frameshift alleles m2/m1/p1/p2.


1 primers derived from SCHWARTZS1999.

SelTarbase version latest, release 201307, last updated 20130701.

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