previous  nextM85079.A10.709 (TGFBR2) -> ENSG00000163513@59_37d.A10.30691872
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Tract / statusA10 / cMNR -> Tx!   MNR_ensembl
First published byLU1995 PubMed
Accession numberM85079 gi:339569
Gene (chromosome)TGFBR2  ( 3 )   SOURCE
alt. namesBATRII;TGFB2R
EnsemblENSG00000163513   SMART   GermOnline   GeneCards
NCBIEntrez Gene 7048   Unigene Hs.604277 (SAGE) Hs.82028 (SAGE)   GeneCards 7048 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
73.885.414.564.5
(n=2983)(n=41)(n=517)(n=840)

Genomic sequence
BLAST WWW
BLAST local
CTCCCTCTCC CCTCGCTTCC AATGAATCTC TTCACTCTAG GAGAAAGAAT GACGAGAACA TAACACTAGA GACAGTTTGC CATGACCCCA AGCTCCCCTA CCATGACTTT ATTCTGGAAG ATGCTGCTTC TCCAAAGTGC ATTATGAAGG AAAAAAAAAA GCCTGGTGAG ACTTTCTTCA TGTGTTCCTG TAGCTCTGAT GAGTGCAATG ACAACATCAT CTTCTCAGAA GGTGAGTTTT CTTCTCTTAA GGGTGTGGGA CCTGAGATCT GTGCCAATTT TTTGTATCCT TGGTCTGCAG TGTCATAGAG
MNR, transcribed, primer.
PCR system1sense gCTgCTTCTCCAAAgTgCAT, antisense CAgATCTCAggTCCCACACC, product length 149, Ta 59.
Transcript sequenceCCATCTGTGA GAAGCCACAG GAAGTCTGTG TGGCTGTATG GAGAAAGAAT GACGAGAACA TAACACTAGA GACAGTTTGC CATGACCCCA AGCTCCCCTA CCATGACTTT ATTCTGGAAG ATGCTGCTTC TCCAAAGTGC ATTATGAAGG AAAAAAAAAA GCCTGGTGAG ACTTTCTTCA TGTGTTCCTG TAGCTCTGAT GAGTGCAATG ACAACATCAT CTTCTCAGAA GAATATAACA CCAGCAATCC TGACTTGTTG CTAGTCATAT TTCAAGTGAC AGGCATCAGC CTCCTGCCAC CACTGGGAGT
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST000002957541138320874621756ENSP00000295754show
2ENST000003590131128420634605732ENSP00000351905show
3ENST000004399251052717212013498ENSP00000392572show
4ENST000003837651076111002385732ENSP00000373275show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: cMNR (cMNR) .

Culture data cell line   mutated   allele(s)  reference
Co115 1 m1* GAYET2001 / *KONRAD9999
Colo60H 1 m2wtp1 KONRAD9999
DLD1 1 m1wt* PARSONS1995B / *YOU2007
HCA7 1 m1* ILYAS1999 / *WILLIAMS2010
HCT C 1 - PARSONS1995B
HCT116 1 m1 WANG1995
HCT15 1 mwt* PARSONS1995B / *ELBCHIRI2005
HCT8/HRT18 1 m1wt* KU1999 / *YOU2007
KM12 1 m1wt* PARSONS1995B / *WOERNER2001
LIM1215 1 m1* HEMPEN2003A / *WILLIAMS2010
LIM1899 1 m2p1 WILLIAMS2010
LIM2405 0 wt WILLIAMS2010
LIM2408 0 wt WILLIAMS2010
LIM2537 1 m2m1 WILLIAMS2010
LIM2550 1 m1wt WILLIAMS2010
LIM2551 1 m1 WILLIAMS2010
LoVo 1 m2m1* PARSONS1995B / *WOERNER2001
LS174T 1 m1* VINCENT1997 / *WOERNER2001
LS180 1 m1* PARSONS1995B / *WOERNER2001
LS411 1 - VINCENT1997
RKO 1 m2m1wt* MARKOWITZ1995 / *KONRAD9999
SNU-1040 0 - KU1999
SNU-1047 1 - KU1999
SNU-1544 1 m1p1 KU2010A
SNU-1684 1 m2 KU2010A
SNU-1746 1 m1 KU2010A
SNU-175 0 - KU1999
SNU-407 1 - KU1999
SNU-769A 1 - KU1999
SNU-769B 1 - KU1999
SNU-C2A 0 - KU1999
SNU-C4 1 wt* KU1999 / *YOU2007
SW48 1 m1* PARSONS1995B / *WOERNER2001
TC7 1 m1* GAYET2001 / *KONRAD9999
TC71 1 m2m1wt* GAYET2001 / *KONRAD9999
VACC1430 1 - HEMPEN2003A
VaCo444 1 - HEMPEN2003A
VaCo457 1 - MARKOWITZ1995
VaCo481 0 - MARKOWITZ1995
VaCo5 1 m2m1* PARSONS1995B / *BAKER2007
VaCo6 1 - PARSONS1995B

Show consequences concerning peptide sequence(s) of frameshift alleles m2/m1/p1/p2.


1 primers derived from WOERNER2005.

SelTarbase version latest, release 201307, last updated 20130701.

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