previous  nextM24350.A11.144 (PTHLH) -> ENSG00000087494@66_37.A11.28114898
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Tract / statusA11 / cMNR -> Tx!   MNR_ensembl
First published byWOERNER2001 PubMed
Accession numberM24350 gi:190709
Gene (chromosome)PTHLH  ( 12 )   SOURCE
alt. namesPTHL3;PTHrP
EnsemblENSG00000087494   SMART   GermOnline   GeneCards
NCBIEntrez Gene 5744   Unigene Hs.591159 (SAGE)   GeneCards 5744 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
76.193.350.073.3
(n=113)(n=30)(n=12)(n=15)

Genomic sequence
BLAST WWW
BLAST local
TTGAAATAGG TGGCCCCAAA GCTGGATTTA TCTCCCTGTT TTCTGACACG TAGACAGTGC TATGTTTGCC CTGCTTCTTT ATCGATGCAT TTCCATTGAA ATGATTTTTT TTTCTTTTCA CTTTTCAGTA CAGCACTTCT GTGGGGTTTG AAAAAAAAAA AGGAAAACAA CAGAAGAACA CATCATATGC AACTAATGAT CTCATTATTT AAGAGTCCCC TGTTACTTCT TTAGTCATTT CCTTTGACTC TGCTACAGAT AGGATTATAG GATGATGCTT CAAAGGGGAC CTTGAACCTA TTCACCATTA T
MNR, transcribed, primer.
PCR system1sense TTTCACTTTCAgTACAgCACTTCTg, antisense gAAgTAACAggggACTCTTAAATAATg, product length 107, Ta 60.
Transcript sequenceAAACTAACAA GGTGGAGACG TACAAAGAGC AGCCGCTCAA GACACCTGGG AAGAAAAAGA AAGGCAAGCC CGGGAAACGC AAGGAGCAGG AAAAGAAAAA ACGGCGAACT CGCTCTGCCT GGTTAGACTC TGGAGTGACT GGGAGTGGGC TAGAAGGGGA CCACCTGTCT GACACCTCCA CAACGTCGCT GGAGCTCGAT TCACGTACAG CACTTCTGTG GGGTTTGAAA AAAAAAAAGG AAAACAACAG AAGAACACAT CATATGCAAC TAATGATCTC ATTATTTAAG AGTCCCCTGT TACTTCTTTA G
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST000005392390068602890ENSP00000441571show
2ENST000005452340054210761214ENSP00000441765show
3ENST00000538310111631854547ENSP00000441890show
4ENST00000535992003488761891ENSP00000440613show
5ENST00000395868003909181674ENSP00000379209show
6ENST0000054296300231750746ENSP00000444519show
7ENST0000053489000125461457ENSP00000445157show
8ENST00000395872003108441318ENSP00000379213show
9ENST0000035441711323953952869ENSP00000346398show
10ENST000005367470018281ENSP00000446431show
11ENST00000201015003238511872ENSP00000201015show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: cMNR (cMNR) .

Culture data cell line   mutated   allele(s)  reference
Co115 1 m2m1wt WOERNER2001
Colo60H 1 m1 WOERNER2001
DLD1 1 m4m1 WOERNER2010
HCA7 1 m2wt WILLIAMS2010
HCT116 1 m2 WOERNER2001
HCT15 1 m4m1 WOERNER2010
HCT8/HRT18 1 m4m1 WOERNER2010
HDC108 1 m2m1wt WOERNER2010
HDC143 0 wt WOERNER2010
HDC9 1 m1 WOERNER2010
K073A_culture 1 m1wt WOERNER2010
KM12 1 m1 WOERNER2001
LIM1215 1 m2m1 WOERNER2010
LIM1899 1 m1wt WILLIAMS2010
LIM2405 1 m1wt WILLIAMS2010
LIM2408 1 m1wt WILLIAMS2010
LIM2537 1 m1wt WILLIAMS2010
LIM2550 1 m1wt WILLIAMS2010
LIM2551 1 m1wt WILLIAMS2010
LoVo 1 m2m1 WOERNER2001
LS174T 1 m1wt WOERNER2001
LS180 1 m1wt WOERNER2001
RKO 0 wt WOERNER2001
SW48 1 m1wt WOERNER2001
TC7 1 m2m1 INTERN9999
TC71 1 m1wt INTERN9999
VaCo432 1 m1wt WOERNER2010
VaCo457 1 m1 WOERNER2010
VaCo5 1 m1wt WOERNER2010
VaCo6 1 m1wt WOERNER2010

Show consequences concerning peptide sequence(s) of frameshift alleles m2/m1/p1/p2.


1 primers derived from WOERNER2001.

SelTarbase version latest, release 201307, last updated 20130701.

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