previous  nextL22473.G8.114 (BAX) -> ENSG00000087088@66_37.G8.49458971
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Tract / statusG8 / cMNR -> Tx!   MNR_ensembl
First published byRAMPINO1997 PubMed
Accession numberL22473 gi:388165
Gene (chromosome)BAX  ( 19 )   SOURCE
alt. namesBAX
EnsemblENSG00000087088   SMART   GermOnline   GeneCards
NCBIEntrez Gene 581   Unigene Hs.631546 (SAGE)   GeneCards 581 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
41.554.824.037.3
(n=2328)(n=31)(n=445)(n=705)

Genomic sequence
BLAST WWW
BLAST local
GCAGATCATG AAGACAGGGG CCCTTTTGCT TCAGGGGTGA GTTTGAGGTC TGATTATTGT GGCACAGATT TGAGGAGTGA CACCCCGTTC TGATTCTGCA CCCTCACTCC ATCCCCACTC TAGTTTCATC CAGGATCGAG CAGGGCGAAT GGGGGGGGAG GCACCCGAGC TGGCCCTGGA CCCGGTGCCT CAGGATGCGT CCACCAAGAA GCTGAGCGAG TGTCTCAAGC GCATCGGGGA CGAACTGGAC AGTAACATGG AGCTGCAGAG GTGTGGGCCC CTGAGGACCC AGAAGTCCAG CCACTGGG
MNR, transcribed, primer.
PCR system1sense ATCCAggATCgAgCAgggCg, antisense ACTCgCTCAgCTTCTTggTg, product length 94, Ta 59.
Transcript sequenceGCGGACCCGG CGAGAGGCGG CGGCGGGAGC GGCGGTGATG GACGGGTCCG GGGAGCAGCC CAGAGGCGGG GGGCCCACCA GCTCTGAGCA GATCATGAAG ACAGGGGCCC TTTTGCTTCA GGGTTTCATC CAGGATCGAG CAGGGCGAAT GGGGGGGGAG GCACCCGAGC TGGCCCTGGA CCCGGTGCCT CAGGATGCGT CCACCAAGAA GCTGAGCGAG TGTCTCAAGC GCATCGGGGA CGAACTGGAC AGTAACATGG AGCTGCAGAG GATGATTGCC GCCGTGGACA CAGACTCCCC CCGAGAGG
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST000005024871001346813--
2ENST000003453581153632793166ENSP00000263262show
3ENST00000513545100775233--
4ENST0000051554011112730062ENSP00000426328show
5ENST00000356483111496677114ENSP00000348871show
6ENST00000415969111541540114ENSP00000389971show
7ENST00000354470001433433ENSP00000346461show
8ENST00000506183003384383ENSP00000426184show
9ENST000002932881116581358114ENSP00000293288show
10ENST00000503726100488207--
11ENST0000051321700869--
12ENST0000050775700580--
13ENST000005397871170565866183ENSP00000441413show
14ENST000003918711150176735111ENSP00000375744show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: cMNR (cMNR) .

Culture data cell line   mutated   allele(s)  reference
Co115 1 m1wt* GAYET2001 / *INTERN9999
Colo60H 0 wt INTERN9999
DLD1 0 - RAMPINO1997
HCA7 1 m1 WILLIAMS2010
HCT116 1 m1wt* RAMPINO1997 / *WOERNER2001
HCT15 0 - GAYET2001
HCT8/HRT18 0 - KU1999
KM12 1 m1wtp1 WOERNER2001
LIM1215 1 m1 WILLIAMS2010
LIM1899 1 m1 WILLIAMS2010
LIM2405 0 wt WILLIAMS2010
LIM2408 0 wt WILLIAMS2010
LIM2537 1 m1wt WILLIAMS2010
LIM2550 0 wt WILLIAMS2010
LIM2551 0 wt WILLIAMS2010
LoVo 1 m1wtp1* RAMPINO1997 / *WOERNER2001
LS174T 1 m1* KU1999 / *WOERNER2001
LS180 1 m1* RAMPINO1997 / *WOERNER2001
LS411 1 - RAMPINO1997
RKO 0 wt ELBCHIRI2005
SNU-1040 1 - KU1999
SNU-1047 1 - KU1999
SNU-175 0 - KU1999
SNU-407 1 - KU1999
SNU-769A 1 - KU1999
SNU-769B 1 - KU1999
SNU-C2A 0 - KU1999
SNU-C4 1 m1wt* KU1999 / *KOH2005
SW48 0 - RAMPINO1997
TC7 0 - GAYET2001
TC71 0 - GAYET2001

Show consequences concerning peptide sequence(s) of frameshift alleles m2/m1/p1/p2.


1 primers derived from RAMPINO1997.

SelTarbase version latest, release 201307, last updated 20130701.

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