previous  nextD10522.A11.823 (MARCKS) -> ENSG00000155130@66_37.A11.114181210
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Tract / statusA11 / cMNR -> Tx!   MNR_ensembl
First published byKIM2002A PubMed
Accession numberD10522 gi:219893
Gene (chromosome)MARCKS  ( 6 )   SOURCE
alt. namesMACS;MACS;KCS
EnsemblENSG00000155130   SMART   GermOnline   GeneCards
NCBIEntrez Gene 4082   Unigene Hs.519909 (SAGE)   GeneCards 4082 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
70.370.625.060.0
(n=118)(n=17)(n=12)(n=15)

Genomic sequence
BLAST WWW
BLAST local
CCGGTAGAGA AGGAGGCCCC CGCGGAAGGC GAGGCTGCCG AGCCCGGCTC GCCCACGGCC GCGGAGGGAG AGGCCGCGTC GGCCGCCTCC TCGACTTCTT CGCCCAAGGC CGAGGACGGG GCCACGCCCT CGCCCAGCAA CGAGACCCCG AAAAAAAAAA AGAAGCGCTT TTCCTTCAAG AAGTCTTTCA AGCTGAGCGG CTTCTCCTTC AAGAAGAACA AGAAGGAGGC TGGAGAAGGC GGTGAGGCTG AGGCGCCCGC TGCCGAAGGC GGCAAGGACG AGGCCGCCGG GGGCGCAGCT GCGGCCGCCG C
MNR, transcribed, primer.
PCR system1sense gACTTCTTCgCCCAAggC, antisense gCCgCTCAgCTTgAAAgA, product length 109, Ta 58.
Transcript sequenceCCGGTAGAGA AGGAGGCCCC CGCGGAAGGC GAGGCTGCCG AGCCCGGCTC GCCCACGGCC GCGGAGGGAG AGGCCGCGTC GGCCGCCTCC TCGACTTCTT CGCCCAAGGC CGAGGACGGG GCCACGCCCT CGCCCAGCAA CGAGACCCCG AAAAAAAAAA AGAAGCGCTT TTCCTTCAAG AAGTCTTTCA AGCTGAGCGG CTTCTCCTTC AAGAAGAACA AGAAGGAGGC TGGAGAAGGC GGTGAGGCTG AGGCGCCCGC TGCCGAAGGC GGCAAGGACG AGGCCGCCGG GGGCGCAGCT GCGGCCGCCG C
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST000003686351138213814273835ENSP00000357624show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: cMNR (cMNR) .

Culture data cell line   mutated   allele(s)  reference
Co115 1 m3m2m1 WOERNER2010
Colo60H 1 m1wt WOERNER2010
DLD1 0 wt YOU2007
HCT116 1 m1wt YOU2007
HCT8/HRT18 0 wt YOU2007
KM12 1 m1wt WOERNER2010
LoVo 1 m1* IVANOV2007 / *YOU2007
LS174T 1 m1 YOU2007
LS180 1 m1* IVANOV2007 / *WOERNER2010
RKO 0 - IVANOV2007
SNU-407 1 m1 KIM2013C
SNU-C2A 1 m2wt YOU2007
SNU-C2B 1 m2wt KIM2013C
SNU-C4 1 m1 YOU2007
SW48 0 - IVANOV2007
TC7 1 m1wt WOERNER2010
TC71 0 wt WOERNER2010

Show consequences concerning peptide sequence(s) of frameshift alleles m2/m1/p1/p2.


1 primers derived from WOERNER2005.

SelTarbase version latest, release 201307, last updated 20130701.

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