previous  nextAF072250.A10.1106 (MBD4) -> ENSG00000129071@66_37.A10.129155548
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Tract / statusA10 / cMNR -> Tx!   MNR_ensembl
First published byRICCIO1999 PubMed
Accession numberAF072250 gi:3800808
Gene (chromosome)MBD4  ( 3 )   SOURCE
alt. namesMBD4;MED1
EnsemblENSG00000129071   SMART   GermOnline   GeneCards
NCBIEntrez Gene 8930   Unigene Hs.35947 (SAGE)   GeneCards 8930 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
24.630.09.920.1
(n=537)(n=20)(n=91)(n=273)

Genomic sequence
BLAST WWW
BLAST local
TGATAGCAAA AGAGAATCTG TGTGTAATAA AGCAGATGCT GAAAGTGAAC CTGTTGCACA AAAAAGTCAG CTTGATAGAA CTGTCTGCAT TTCTGATGCT GGAGCATGTG GTGAGACCCT CAGTGTGACC AGTGAAGAAA ACAGCCTTGT AAAAAAAAAA GAAAGATCAT TGAGTTCAGG ATCAAATTTT TGTTCTGAAC AAAAAACTTC TGGCATCATA AACAAATTTT GTTCAGCCAA AGACTCAGAA CACAACGAGA AGTATGAGGA TACCTTTTTA GAATCTGAAG AAATCGGAAC AAAAGTAGAA
MNR, transcribed, primer.
PCR system1sense TgACCAgTgAAgAAAACAgCC, antisense gTTTATgATgCCAgAAgTTTTTTg, product length 98, Ta 60.
Transcript sequenceTGATAGCAAA AGAGAATCTG TGTGTAATAA AGCAGATGCT GAAAGTGAAC CTGTTGCACA AAAAAGTCAG CTTGATAGAA CTGTCTGCAT TTCTGATGCT GGAGCATGTG GTGAGACCCT CAGTGTGACC AGTGAAGAAA ACAGCCTTGT AAAAAAAAAA GAAAGATCAT TGAGTTCAGG ATCAAATTTT TGTTCTGAAC AAAAAACTTC TGGCATCATA AACAAATTTT GTTCAGCCAA AGACTCAGAA CACAACGAGA AGTATGAGGA TACCTTTTTA GAATCTGAAG AAATCGGAAC AAAAGTAGAA
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST00000393278001790804ENSP00000376959show
2ENST0000050958700643--
3ENST0000050588300613--
4ENST0000051526600434--
5ENST0000051100900530--
6ENST0000050720811203192221941132ENSP00000422327show
7ENST000005098280095254576ENSP00000422690show
8ENST0000050319711175179820991104ENSP00000424873show
9ENST0000024991011177192024701106ENSP00000249910show
10ENST0000042954411197192224781126ENSP00000394080show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: cMNR (cMNR) .

Culture data cell line   mutated   allele(s)  reference
Co115 0 wt WOERNER2001
Colo60H 0 wt WOERNER2001
HCA7 1 m1 ABDELRAHMAN2008A
HCT116 1 m1wt WOERNER2001
HCT15 0 wt ABDELRAHMAN2008A
KM12 0 wt WOERNER2001
LIM1215 0 wt ABDELRAHMAN2008A
LIM1899 1 m1wt WILLIAMS2010
LIM2405 0 wt WILLIAMS2010
LIM2408 0 wt WILLIAMS2010
LIM2537 1 m1wt WILLIAMS2010
LIM2550 1 m1wt WILLIAMS2010
LIM2551 0 wt WILLIAMS2010
LoVo 0 wt WOERNER2001
LS174T 0 wt WOERNER2001
LS180 0 wt WOERNER2001
RKO 0 wt WOERNER2001
SW48 0 wt WOERNER2001
TC7 0 wt INTERN9999
TC71 1 wtp1 INTERN9999

Show consequences concerning peptide sequence(s) of frameshift alleles m2/m1/p1/p2.


1 primers derived from WOERNER2001.

SelTarbase version latest, release 201307, last updated 20130701.

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