previous  nextAF024714.A10.1263 (AIM2) -> ENSG00000163568@66_37.A10.159032487
         ? HELP ?
Tract / statusA10 / cMNR -> Tx!   MNR_ensembl
First published byMORI2001A PubMed
Accession numberAF024714 gi:2558941
Gene (chromosome)AIM2  ( 1 )   SOURCE
alt. namesAIM2
EnsemblENSG00000163568   SMART   GermOnline   GeneCards
NCBIEntrez Gene 9447   Unigene Hs.281898 (SAGE)   GeneCards 9447 

Mutation rate [%] Colon Endometrium Stomach Urothel
Cancer Adenoma Culture Cancer Cancer Cancer
51.764.350.033.3
(n=174)(n=28)(n=12)(n=33)

Genomic sequence
BLAST WWW
BLAST local
AATGTATTAG AAGGGTGGGA ACAAAATAAT TTTATGAGAA GATGATACAT ACACTTCAGA AGGCCATAGT GACTGCAAAC AGTGGAGGGG CCACTCATCG ACTGCATCTC AGACTGCATG TTTTTTTTCT CCATCCAGGT TATTAAGGCC AAAAAAAAAA CATAGAGAAG TAAAAAGGAC CAATTCAAGC CAACTGGTCT AAGCAGCATT TAATTGAAGA ATATGTGATA CAGCCTCTTC AATCAGATTG TAAGTTACCT GAAAGCTGCA GTTCACAGGC TCCTCTCTCC ACCAAATTAG GATAGAATAA
MNR, transcribed, primer.
PCR system1sense TTCTCCATCCAggTTATTAAggC, antisense TTAgACCAgTTggCTTgAATTg, product length 76, Ta 60.
Transcript sequenceAAAATGGAAG TACTGGGGGT TAGAAACGAG GACACAATGA AATGTAAGGA AGGAGATAAG GTTCGACTTA CATTCTTCAC ACTGTCAAAA AATGGAGAAA AACTACAGCT GACATCTGGA GTTCATAGCA CCATAAAGGT TATTAAGGCC AAAAAAAAAA CATAGAGAAG TAAAAAGGAC CAATTCAAGC CAACTGGTCT AAGCAGCATT TAATTGAAGA ATATGTGATA CAGCCTCTTC AATCAGATTG TAAGTTACCT GAAAGCTGCA GTTCACAGGC TCCTCTCTCC ACCAAATTAG GATAGAATAA
MNR, homologue to genomic MNR region.
Transcripts#ENSTtranscribedtranslatedATGSTOPlengthMNRENSPlocate
1ENST0000036813011290132215291307ENSP00000357112show
2ENST0000048182900508--
3ENST000003681290094598594ENSP00000357111show
4ENST0000041176800423834832ENSP00000405197show
Shown are all Ensembl transcripts (ENSTs) currently annotated for the respective Ensembl gene (ENSG), Ensembl rel. 66_37.
final status: cMNR (cMNR) .

Culture data cell line   mutated   allele(s)  reference
Colo60H 1 m2wt WOERNER2007
DLD1 1 m1wt KIM2013C
HCA7 1 m1wt WILLIAMS2010
HCT116 1 m1 WOERNER2007
HCT8/HRT18 0 wt WOERNER2007
KM12 0 wt WOERNER2007
LIM1215 1 m1wt WILLIAMS2010
LIM1899 0 wt WILLIAMS2010
LIM2405 0 wt WILLIAMS2010
LIM2408 1 m1wt WILLIAMS2010
LIM2537 1 m2m1 WILLIAMS2010
LIM2550 1 m2m1 WILLIAMS2010
LIM2551 1 m1wt WILLIAMS2010
LoVo 1 m1 WOERNER2007
LS174T 0 wt WOERNER2007
LS180 0 wt WOERNER2007
RKO 1 m1wtp1 WOERNER2007
SNU-407 0 wt KIM2013C
SNU-C2A 1 m2m1 KIM2013C
SNU-C2B 1 m2m1 KIM2013C
SNU-C4 0 wt KIM2013C
SW48 1 m1wt WOERNER2007
TC7 0 wt WOERNER2007
TC71 1 m2m1wt WOERNER2007
VaCo432 1 m2m1 WOERNER2007
VaCo457 1 m1wt WOERNER2007
VaCo5 1 m2wt WOERNER2007
VaCo6 0 wt WOERNER2007

Show consequences concerning peptide sequence(s) of frameshift alleles m2/m1/p1/p2.


1 primers derived from WOERNER2005.

SelTarbase version latest, release 201307, last updated 20130701.

? HELP ?